SimTech PN2-2

Data- and Model-Driven Multiscale Simulation of Tumor Growth in Liver Cell, Tissue and Organ

This project is part of the Project Network 2: In Silico Models of Coupled Biological Systems of the Cluster of Excellence "Data-Integrated Simulation Science (SimTech)" and thus funded by Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany´s Excellence Strategy – EXC 2075 – 390740016.  

The project aims at a better understanding of the development of tumors in the liver, which is necessary to predict the process of cancer growth and retardation in the liver. The scope is as follows:

  1. Develop a deterministic multiscale model for tumor growth and metastases,
  2. improve the efficiency in the numerical calculation,
  3. integrate data obtained experimentally and in silico, and
  4. develop and apply polymorphic uncertainty quantification (UQ) procedures.

Further information: https://www.simtech.uni-stuttgart.de/exc/research/pn/pn2/pn2-2a/

Publications

  1. 2023

    1. Suditsch, M., Ricken, T., & Wagner, A. (2023). Patient-specific simulation of brain tumour growth and regression. PAMM, 23(1), Article 1. https://doi.org/10.1002/pamm.202200213
  2. 2021

    1. Suditsch, M., Lambers, L., Ricken, T., & Wagner, A. (2021). Application of a continuum-mechanical tumour model to brain tissue. PAMM, 21(1), Article 1. https://doi.org/10.1002/pamm.202100204
This image shows Navina Waschinsky

Navina Waschinsky

Dr.-Ing.

Head of Optimization & Uncertainty Quantification Group, Researcher

This image shows Tim Ricken

Tim Ricken

Univ.-Prof. Dr.-Ing.

Head of Department

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